26: Let’s Talk HRT - The Risks & Benefits
🫠 If you’ve ever wondered whether hormone replacement therapy is dangerous, risky, life-changing, or something you should avoid, today’s episode brings clarity, truth, and evidence.
👩🏻🏫 In this episode of The Carly Bayless Podcast, I explore HRT through the lens of the WorldLink Medical / Neal Rouzier framework — one of the most evidence-based, data-driven approaches to hormone optimization.
I break down:
The origins of HRT fear (Hello Women’s Health Initiative)
The difference between synthetic and bioidentical hormones
Why the form of estrogen matters (transdermal vs oral)
Why progesterone is protective, not dangerous
Which hormones reduce disease risk
Who is a good candidate for HRT
Why timing is crucial
And how I monitor hormones for long-term safety and efficacy
You’ll also learn exactly how I approach HRT in clinical practice:
🔬 Bloodwork 3–4 times per year
🧪 Annual DUTCH testing (once stable)
📊 Tracking symptom changes over time
⚖️ Staying in physiologic ranges (never supraphysiologic)
🧍🏻♀️ Personalized dosing based on your body’s response
👩⚕️ Collaboration with existing medical providers
📈 Long-term monitoring of metabolic and inflammatory markers
This episode will leave you feeling informed, reassured, and empowered - not afraid of HRT, but confident in navigating it with intention and support.
✨ KEY TAKEAWAYS
Bioidentical hormones are not the same as synthetic
Estradiol, when used transdermally, is protective
Progesterone supports sleep, mood, and breast health
HRT reduces all-cause mortality and supports longevity
The risks are primarily tied to the wrong forms of hormones
Ongoing monitoring is KEY to safe, effective HRT
You don’t have to “age quietly” or “suffer through menopause”
You’re allowed to feel like yourself again (no need to engage in the “Struggle Olympics” as @thewallertribe)
💛 RESOURCES & LINKS
Learn more about Nurture Functional Medicine
Follow NFM (@nurturefunctionalmedicine) and Carly on Instagram (@carlybaylesswellness)
HRT series episodes (upcoming)- stay tuned!
Progesterone
Estradiol
Thyroid
Testosterone
DHEA
🙋♀️ WANT HELP?
If you’re curious about HRT, or want to explore a monitored and individualized approach, we’d love to support you. Schedule a free discovery call with us at Nurture Functional Medicine.

